那夜凌晨，我坐上了旺角开往大埔的红VAN

小职员阿池（黄又南 饰）于凌晨坐上了一辆由九龙旺角开网新界大埔的红色小巴士，车上有司机肥雪（林雪 饰）、义气大叔黄万发（任达华 饰）、神婆（惠英红 饰）、IT男阿信（徐天佑 饰）以及美女Yuki（文咏珊 饰）、吸毒佬（李灿森 饰）等17人。原本平静的夜晚，在小巴穿过狮子山隧道后突然被打破，众人发现除了车上的乘客，全香港的居民仿佛都消失了，一系列的神秘事件接踵而至，大家惊恐之余决定打造统一阵线，以解救自己开启谜团。A night like any other in the streets of Hong Kong: in the midst of the tangle of night-owls, cars and vendors, a group of passengers climb aboard a minibus that is to take them from Mongkok to Tai Po. The group is as diverse as the city: there's a young man on drugs, an arguing couple, a woman with prayer beads and a girl who has just fallen in love, and behind the wheel sits the chatty driver. As the bus emerges from a tunnel, everything is suddenly quite still: the streets and buildings are all empty and there's not a soul to be seen; it's as if everyone has suddenly been swallowed by the earth. Only the millions of neon lights continue to blink, as if nothing has happened. The eclectic group of passengers seek refuge in a deserted café and discuss what they should do. Then they make a horrific discovery.